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CRI Research in brief
CRI Research Collaboratory is a research unit of INSERM and University of Paris (UMR U1284), working at the crossroads of life, learning, and digital sciences.

Founded in the spirit of facilitating the transition from closed scientific enquiry to a more open model we aim to transcending barriers between disciplines, science and the society.

We foster research at crossroads between interdisciplinary life and health sciences, basic understanding of learning processes and novel education technology/methodology testing and implementation, and digital sciences.

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Monday, January 25, 2021
11:30 AM
CRI Research Seminar: Pauline Provini

Birdsong for human(e) voices We share remarkable similarities with birds. Among them, bipedalism and complex language are two traits often seen as human specificities, yet also present in birds. In my long-term fellow project, I want to focus on birdsong to build a new generation of vocal prostheses. Patients suffering from an advanced stage of laryngeal cancer often have to undergo a total surgical removal of the larynx, which is the human voice source. To recover the ability to speak, a prosthesis, mimicking the vocal folds, is usually placed between the trachea and the oesophagus. The exhaled air crosses a vibrating element and produces a substitute voice. Unfortunately, the created voice is of poor quality: it is weak, with a low pitch and sounds mechanical. In addition, the limited lifetime of the devices, due to biofilm coming from mucus/material interactions, forces a frequent device replacement. To date, there is no voice prosthesis lasting more than 3 months and able to reconstruct a natural-sounding human voice. In this context, birds should attract attention. First, their vocal repertoire is incredibly diverse, with pitches spanning from 100 to 12 000 Hz, compared to only 85 to 255 Hz in human speech. Moreover, their unique vocal organ, the syrinx, produces sounds from the vibration of membranes, located in the wall of the syrinx, unlike in mammals. Finally, birds modulate the primary sound with motions of the entire vocal tract, which is probably linked to the diversity of sounds they are able to produce. By exploring the anatomy of the vocal system in a broad range of birds species, and quantifying the 3D motions of the vocal system during sound production and modulation, we want to build a predictive aero-acoustic model we can use to ask “what if” questions and understand cause-effect relationships between shape, motions, and produced sounds. I will present the interdisciplinary approach we use in the CRI Birdsong team, integrating biology, physics, and computer science to provide the fundamental principles to the design of a new generation of vocal prostheses that will produce voices that sound more humane.

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Sunday, January 31, 2021
10:00 AM
Ateliers Sciences Marines by Astrolabe Expeditions

Atelier de construction de kit de mesure océanographique qui partiront sur des voiliers de plaisance pour des expéditions scientifiques en mer.

CRI Project : Phd Project : https://projects.cri-paris.org/projects/1YVgcwH0/summary

Astrolabe Expeditions https://projects.cri-paris.org/projects/VmcqjP7a/summary

Projet SensOcean : http://www.astrolabe-expeditions.org/programme-de-sciences/sensocean/

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Monday, February 8, 2021
11:30 AM
CRI Research Seminar: Marc Santolini

The networks underlying collaborative learning and solving

In this talk, we will present recent advances from our team at the Interaction Data Lab, where we use network science and data analysis to decipher collective phenomena at biological and social scales. In particular, we will showcase projects where we analyse collaborative learning and solving using network approaches on large empirical datasets, with the end goal to develop tools fostering collective intelligence for social impact.

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Monday, February 22, 2021
11:30 AM
CRI Research Seminar: Jake Wintermute

Distributed Approaches to Teaching and Doing Synthetic Biology

Emerging applications of synthetic biology promise major changes in medicine, food, ecology and other domains. Even as the impacts of genetic technologies become more diverse and widespread, the institutions that develop them remain homogenous and centralized. The result is substantial public opposition to many new biotechnologies.

What if we, the scientific experts, are doing everything wrong? This talk will be a conversation about strategies for including more people in the process of doing research and in setting research priorities. Who should be doing synthetic biology and what are their motivations for doing so? How can we balance expert knowledge with public values? What would a popular version of biotechnology look like and what would it take to transition from our current practices?

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Monday, March 8, 2021
11:30 AM
CRI Research Seminar: Roberto Toro


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